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1 News interviews MRINZ Director Professor Richard Beasley

1 News interview MRINZ director about “ground-breaking” asthma research which could more than half risk of severe exacerbations

May 21, 2019

1 in 6 New Zealanders has asthma, and many require two inhalers - a 'preventer' and a 'reliever'. Increased treatment complexity has been shown to reduce adherence to that prescription - which could nullify any benefit. 1 News interviewed MRINZ director Professor Richard Beasley about the recent publication of ground-breaking asthma research, which showed a combination inhaler could more than half the risk of severe asthma exacerbations. This benefit came with a lower number of inhalers, less frequent doses, and a lower overall steroid burden. The study was published in the New England Journal of Medicine.

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Kanuka honey cold sore treatment editorial illustration by Dr Ciléin Kearns

Kānuka honey found as effective as standard anti-viral treatment for cold sores, in large-scale randomised controlled trial

A unique pharmacy-backed trial, one of the largest medical studies of its kind ever undertaken in this country, has shown that honey derived from the New Zealand kānuka tree is just as effective in healing cold sores as standard pharmaceutical anti-viral treatment. The results published in the prestigious British Medical Journal Open, has shown that a New Zealand kānuka honey formulation Honevo (90% kānuka honey and 10% glycerin) is as effective as Viraban (5% aciclovir cream) in the time it takes to reduce pain and heal a cold sore. Dr Alex Semprini who led the study, says it’s unusual for...

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NIV vs NHF COPD illustration by Dr Cilein Kearns Artibiotics

NIV vs NHF for hypercapnic respiratory failure in COPD

May 20, 2019

Our latest study compared the current "Gold Standard" treatment in COPD: Non-Invasive Ventilation (NIV, which can be poorly tolerated in up to 20% of patients) against a possible future alternative strategy of Nasal High-Flow Oxygen (NHF). Check out Dr Steven McKinstry presenting a short video summary of this publication in Respirology. The bottom line, according to co-author Dr James Fingleton, was that "NHF is a potential new treatment option for people with COPD and hypercapnic respiratory failure which may be better tolerated than the current gold-standard treatment, but we need trials comparing the two treatments over longer periods of time in people's...

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Kia Kaha New Zealand by Cilein Kearns (Artibiotics)

Kia kaha, Christchurch

March 18, 2019

All of us at the Institute are saddened and shocked by the terrible events in Christchurch on Friday 15th March 2019. Our thoughts go out to all those affected directly and we share the determination to stand strong with all New Zealanders in the face of such actions. Kia Kaha. (Illustration by Artibiotics)

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Diagnostic labelling versus the treatable trait approah: diagram from our latest ERJ publication - Letting the right one in: evaluating the generalisability of clinical trials

Letting the right one in: evaluating the generalisability of clinical trials

December 16, 2018

"Diagnostic labelling" harms targeted therapy research in airways disease. We make a call to adopt the "treatable trait" approach with our latest publication in the European Respiratory Journal: http://erj.ersjournals.com/content/52/6/1802218 Shrimanker R, Beasley R, Kearns C. Letting the right one in: evaluating the generalisability of clinical trials. Eur Respir J 2018; 52: 1802218 [https://doi.org/10.1183/13993003.02218- 2018].

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Video podcast: NZ Adult Asthma Guidelines: A Quick Reference Guide.

November 21, 2018

Research Review has published a new video podcast providing an outline of the NZ Adult Asthma Guidelines published in November 2016. The presentation is by Professor Richard Beasley, Physician at Wellington Regional Hospital, and Director of the Medical Research Institute of New Zealand. The purpose of the Asthma Foundation of New Zealand Quick Reference Guide is to provide simple, practical, evidence-based recommendations for the diagnosis, assessment and management of asthma in adults in a quick reference format. Professor Beasley also focuses on the changes to the guidelines since they were last updated in 2002. You can watch the video podcast here: https://www.researchreview.co.nz/nz/Pages/podcasts-details-public.aspx?site=nz&pid=76  

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Healthy vs COPD lungs.

Our latest COPD publication featured on national News

October 17, 2018

Our latest publication on COPD treatment was discussed on Newshub's 6pm national news. You can watch the segment here (skip to 20:36): https://www.threenow.co.nz/shows/newshub-6pm/tuesday-16-october-2018/122217/M25466-114 and read the open-access publication here: https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-018-0720-7

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repeated oxygen-driven nebulisation leads to a clinically relevant increase in blood carbon dioxide levels in acute exacerbations of COPD, a new study from MRINZ finds

Oxygen-driven nebulisation leads to clinically relevant rise in blood carbon dioxide in acute exacerbation of COPD

October 15, 2018

A new study from MRINZ has demonstrated that repeated oxygen-driven nebulisation leads to a clinically relevant increase in blood carbon dioxide levels in acute exacerbations of COPD, compared to air-driven nebulisation. You can read the full open-access paper here: https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-018-0720-7

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PIPPA Tamariki milestone: 250 recruited

PIPPA Tamariki milestone: 250 recruited!

October 14, 2018

PIPPA bear is delighted to announce that the PIPPA Tamariki team has reached a new recruitment milestone of 250 Tamariki! Thank you to all the PIPPA Tamariki whānau taking part in this important study on childhood asthma. Well done also to our teams at Wellington, Auckland, and Middlemore hospitals for helping reach this milestone. Click here to find out more about the study. Onwards!

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PIPPA bear teams up with kiwi mums to crack the case on asthma

PIPPA bear teams up with kiwi kids to crack the case on asthma…

September 9, 2018

Introducing PIPPA bear, our new mascot for the PIPPA Tamariki study, which is investigating the potential role of fever medicines in the development of childhood asthma. Read more about the study here: https://pippatamariki.ac.nz/2018/09/05/pippa-bear-teams-up-with-kiwi-kids-to-crack-the-case-on-asthma/

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